The Institut Pasteur du Cambodge (IPC), created in December 1953, is a non-profit research institution operating under the high patronage of the Cambodian Ministry of Health (MoH). Our mission is to contribute to the prevention and treatment of infectious diseases through research, public health activities, and training. This report presents the Institute’s activities in 2023, a year marked by the celebration of the IPC’s 70th anniversary.
As of 31 December 2023, the IPC’s on-site staff represented 16 different nationalities. Scientific activities are carried out by more than 35 scientists, each holding at least a PhD or a doctorate degree in medicine, veterinary medicine or pharmacy and another PhD or master’s degree.
The IPC’s activities encompass four main categories: (i) biomedical research with a specialization in infectious diseases, (ii) support and capacity building for public health in Cambodia and the Greater Mekong Subregion, (iii) the provision of health services (laboratory, vaccination), and (iv) training and education. The IPC focuses on infectious diseases and on public health challenges and issues, which include illnesses related to arboviruses, respiratory viruses, rabies, malaria, antimicrobial resistance in microorganisms, and zoonoses, among others. These complex scientific matters, particularly those that involve pathogens with complex life cycles that can involve humans, mammals, and arthropods — studied with a One Health approach — could not be effectively addressed without complementarity between the Institute’s units and specialists (entomologists, doctors, veterinary scientists, immunologists, epidemiologists, mammalogists and others) or without its high-level technical platforms, including a Biosafety Level-3 (BSL3) laboratory and an animal research facility.
Research activities done in 2023 were featured in 49 articles published by scientists affiliated to IPC, appearing in peer-reviewed international journals with impact factors (IF) greater than 0. Among them are 18 as first or last author and 36 with an IF greater than or equal to 4.
The IPC’s three WHO reference centres carried out public health activities alongside and in support of MoH teams, including: (i) monitoring human and avian influenza viruses (six human cases of highly pathogenic avian influenza virus H5N1), (ii) monitoring SARS-CoV2 variants, and (iii) the virological confirmation of a case of monkeypox virus infection (an imported case from Thailand).
Post-exposure rabies management activities decreased slightly in 2023, by -4,1% compared to 2022, with the management of 60,476 patients in our 3 rabies prevention centres. The risks related to rabies indeed remain high in Cambodia: 74 % of the 220 animals tested for rabies virus at the Virology Unit were positive.
The IPC plays a major role in the training of university students. Its scientists participate in curricula offered by local universities, including the University of Health Sciences (UHS) in Phnom Penh. Additionally, the IPC itself welcomes many students for internships and practical experiences. During 2023, 131 students interned at the IPC. This is higher than the 73 welcomed in 2022, a year which saw a progressive return to normalcy after the COVID-19 pandemic. Among the 131 students, 95 were Cambodian nationals, while the others were French, American, Bangladeshi, Colombian, Cameroonian, Dutch, Pakistani, Kenyan, Italian, and Ugandan.
An ambitious capacity-strengthening policy for young Cambodians was put in place in 2022 (for young talents at the IPC), allowing them to carry out their doctorate studies at the IPC (scholarships for non-IPC students and continued salaries for IPC personnel). This policy continued throughout 2023. As a result, the IPC hosted sixteen doctoral students in the last quarter of 2023, including eight Cambodian nationals.
Our Health Service activities in 2023 compared well to those of 2022: (i) our Medical Biology Laboratory’s activities decreased by 25.5 % (6.2 vs 8 million of “B”), but if we exclude COVID-19 tests, the activity level increased by 53.1 % (5.9 vs 3.8 million of “B”); (ii) a 0.3 % increase for the total number of tests performed by for the Laboratory of Environment and Food Safety; and (iii) a 24 % increase for the total number of injections (including vaccinations and immunoglobulins) provided by the International Vaccination Centre.
Bernard C, Font H, Zotova N, Wools-Kaloustian K, Goodrich S, Kwobah EK, Awoh AR, Nko’o Mbongo’o GC, Nsonde DM, Gandou P, Minga A, Tine JM, Ndiaye I, Dabis F, Seydi M, de Rekeneire N, Yotebieng M, Jaquet A; IeDEA Cohort Collaboration.
J Acquir Immune Defic Syndr. 2024 Oct 24. doi: 10.1097/QAI.0000000000003551.
A genotyping array for the globally invasive vector mosquito, Aedes albopictus
Luciano Veiga Cosme, Margaret Corley, Thomas Johnson, Dave W. Severson, Guiyun Yan, Xiaoming Wang, Nigel Beebe, Andrew Maynard, Mariangela Bonizzoni, Ayda Khorramnejad, Ademir Jesus Martins, José Bento Pereira Lima, Leonard E. Munstermann, Sinnathamby N. Surendran, Chun-Hong Chen, Kevin Maringer, Isra Wahid, Shomen Mukherjee, Jiannon Xu, Michael C. Fontaine, Elizabet L. Estallo, Marina Stein, Todd Livdahl, Patricia Y. Scaraffia, Brendan H. Carter, Motoyoshi Mogi, Nobuko Tuno, James W. Mains, Kim A. Medley, David E. Bowles, Richard J. Gill, Roger Eritja, Ranulfo González-Obando, Huynh T. T. Trang, Sébastien Boyer, Ann-Marie Abunyewa, Kayleigh Hackett, Tina Wu, Justin Nguyễn, Jiangnan Shen, Hongyu Zhao, Jacob E. Crawford, Peter Armbruster & Adalgisa Caccone
Parasites & Vectors volume 17, Article number: 106 (2024) Published: 04 March 2024
https://doi.org/10.1186/s13071-024-06158-z
Mallorie Hide, Pierre-Olivier Maquart, Sony Yean, Kimhuor Suor, Kimly Heng, Saoya Sen, Chanmuneneath Yim, Sokkeang Leng, Antsa Rakotonirina, Didier Fontenille, Sebastien Boyer
Journal of Asia-Pacific Entomology, Volume 27, Issue 2, June 2024, 102233 https://doi.org/10.1016/j.aspen.2024.102233
Antibiotic resistance profiles of sentinel bacteria isolated from aquaculture in Cambodia.
Peng C, Moniroth S, Khy P, Chea S, Thanh C, Heng O, Sarter S, Cheng S, Caruso D.
J Water Health. 2024 Jun;22(6):1033-1043. doi: 10.2166/wh.2024.101. Epub 2024 May 8.
PMID: 38935454, https://doi.org/10.2166/wh.2024.101
Balancing functions of regulatory T cells in mosquito-borne viral infections
Sotheary Sann, Markus Kleinewietfeld, Tineke Cantaert
Emerging Microbes & Infections 2024, https://doi.org/10.1080/22221751.2024.2304061
Auerswald H, Guillebaud J, Durand B, Le Vu M, Sorn S, In S, Pov V, Davun H, Duong V, Ly S, Dussart P, Chevalier V.
PLoS Negl Trop Dis. 2024 Apr 18;18(4):e0012089. doi: 10.1371/journal.pntd.0012089. eCollection 2024 Apr. PMID: 38635851
Sony Yean, Didot Budi Prasetyo, Sebastien Marcombe, Upik Kesumawati Hadi,
Abdul Rahman Kazim, Sonthaya Tiawsirisup, Vu Duc Chinh, Keita Matsuno, Van
Lun Low, Sarah Bonnet, Nathalie Boulanger, Tommy Tsan-Yuk Lam, Mohammad
Yazid Abdad, Vincent Herbreteau, Jean-Marc Chavatte, Samuth Sum,
Theary Ren, Anavaj Sakuntabhai, Pierre-Olivier Maquart, Antsa Rakotonirina,
Sebastien Boyer.
Dreyfus A, Volasoa MH, Guis H, Razafindraibe NP, Razafindramparany MH, Arivony NL, Rakotondrabe N, Andriamananjara MA, Dussart P, Kassie D, Lacoste V, Andriamandimby SF.
Front Vet Sci. 2024 Feb 28;11:1270547. doi: 10.3389/fvets.2024.1270547. eCollection 2024. PMID: 38487708
Climate-driven models of leptospirosis dynamics in tropical islands from three oceanic basins.
Douchet L, Menkes C, Herbreteau V, Larrieu J, Bador M, Goarant C, Mangeas M.
PLoS Negl Trop Dis. 2024 Apr 25;18(4):e0011717. doi: 10.1371/journal.pntd.0011717. Online ahead of print. PMID: 38662800
Hide M, Meng S, Cheng S, Bañuls AL, Ky S, Chantana Y, Laurent D, Delvallez G.
J Glob Antimicrob Resist. 2024 Jul 12:S2213-7165(24)00134-6. doi: 10.1016/j.jgar.2024.06.017. Online ahead of print. PMID: 39004342
Kepple D, Ford CT, Williams J, Abagero B, Li S, Popovici J, Yewhalaw D, Lo E.
PLoS Negl Trop Dis. 2024 Jan 29;18(1):e0011926. doi: 10.1371/journal.pntd.0011926. Online ahead of print.
Comparing malaria risk exposure in rural Cambodia population using GPS tracking and questionnaires.
Pepey A, Souris M, Kim S, Obadia T, Chy S, Ea M, Ouk S, Remoue F, Sovannaroth S, Mueller I, Witkowski B, Vantaux A.
Malar J. 2024 Mar 12;23(1):75. doi: 10.1186/s12936-024-04890-6. PMID: 38475843
Pestana K, Ford A, Rama R, Abagero B, Kepple D, Tomida J, Popovici J, Yewhalaw D, Lo E.
J Infect Dis. 2024 Aug 5:jiae388. doi: 10.1093/infdis/jiae388. Online ahead of print.
PMID: 39102894
d’Elbée M, Harker M, Mafirakureva N, Nanfuka M, Huyen Ton Nu Nguyet M, Taguebue JV, Moh R, Khosa C, Mustapha A, Mwanga-Amumpere J, Borand L, Nolna SK, Komena E, Cumbe S, Mugisha J, Natukunda N, Mao TE, Wittwer J, Bénard A, Bernard T, Sohn H, Bonnet M, Wobudeya E, Marcy O, Dodd PJ; TB-Speed Health Economics Study Group.
EClinicalMedicine. 2024 Mar 21;70:102528. doi: 10.1016/j.eclinm.2024.102528. eCollection 2024 Apr. PMID: 38685930
Dramane Kania, Janin Nouhin, Karine Bolloré, Richard Njouom, Thomas d’Aquin Toni, Almoustapha Issiaka Maiga, Coumba Toure-Kane, Nicole Ngo-Giang-Huong, Anoumou Dagnra, Duy Hoang Chuong Le, Françoise Lunel-Fabiani, Joany Castera-Guy, Pierre Alain Rubbo, Amandine Pisoni, Jean-Christophe Plantier, Edouard Tuaillon
Clinical Microbiology and Infection – Available online 11 May 2024.
https://doi.org/10.1016/j.cmi.2024.05.002.PMID: 38735369
Ebola-specific therapeutic antibodies from lab to clinic: The example of ZMapp.
Wong G, Bienes KM, Xiii A, Fausther-Bovendo H, Kobinger GP.
Antiviral Res. 2024 Apr 3:105873. doi: 10.1016/j.antiviral.2024.105873. Online ahead of print.
PMID: 38580170 Review.
Wobudeya E, Nanfuka M, Ton Nu Nguyet MH, Taguebue JV, Moh R, Breton G, Khosa C, Borand L, Mwanga-Amumpaire J, Mustapha A, Nolna SK, Komena E, Mugisha JR, Natukunda N, Dim B, de Lauzanne A, Cumbe S, Balestre E, Poublan J, Lounnas M, Ngu E, Joshi B, Norval PY, Terquiem EL, Turyahabwe S, Foray L, Sidibé S, Albert KK, Manhiça I, Sekadde M, Detjen A, Verkuijl S, Mao TE, Orne-Gliemann J, Bonnet M, Marcy O; TB-Speed Decentralisation study group.
EClinicalMedicine. 2024 Mar 21;70:102527. doi: 10.1016/j.eclinm.2024.102527. eCollection 2024 Apr. PMID: 38685921
Melingui, B. F ; Leroy-Terquem, E.; Palmer, M.; Taguebue, J-V.; Wachinou, A. P.; Gaudelus, J.; Salomao, A.; Bunnet, D.; Eap, T. C.; Borand, L.; Chabala, C. ; Khosa, C.; Moh, R. ; Mwanga-Amumpere, J.; Eang, M. T.; Manhiça, I. ; Mustapha, A. ; Beneteau, S. ; Falzon, L. ; Seddon, J. A. ; Berteloot, L. ; Wobudeya, E.; Marcy, O. ; Bonnet, M. ; Norval, P. Y.
IJTLD OPEN, Volume 1, Number 2, 1 February 2024, pp. 76-82(7) https://doi.org/10.5588/ijtldopen.23.0484
Officer K, Walker TM, Cheng S, Heng S, Hidé M, Bañuls AL, Cracknell J, Broadis N, Thy N, Abraham S, Warren K, Jackson B.
Sci Rep. 2024 Mar 28;14(1):7343. doi: 10.1038/s41598-024-57318-1. PMID: 38538629
de Block T, De Baetselier I, Van den Bossche D, Abdellati S, Gestels Z, Laumen JGE, Van Dijck C, Vanbaelen T, Claes N, Vandelannoote K, Kenyon C, Harrison O, Santhini Manoharan-Basil S.
J Med Microbiol. 2024 Aug;73(8). doi: 10.1099/jmm.0.001871. PMID: 39212029
Buultjens AH, Vandelannoote K, Mercoulia K, Ballard S, Sloggett C, Howden BP, Seemann T, Stinear TP.
Appl Environ Microbiol. 2024 Jan 30:e0129223. doi: 10.1128/aem.01292-23. Online ahead of print.
Sann S, Heng B, Vo HTM, Arroyo Hornero R, Lay S, Sorn S, Ken S, Ou TP, Laurent D, Yay C, Ly S, Dussart P, Duong V, Sakuntabhai A, Kleinewietfeld M, Cantaert T.
mBio. 2024 May https://doi.org/10.1128/mbio.00063-24 . PMID: 38752787
Ingrained: Rice farming and the risk of zoonotic spillover, examples from Cambodia.
Sievers BL, Hyder S, Claes F, Karlsson EA.
One Health. 2024 Feb 29; eCollection 2024 Jun. PMID: 39010950
Sophea Iv, Chea Nguon, Phanith Kong, Téphanie Siena, Sreynet Srun, Céline Christiansen-Jucht, Chanvong Kul, Thornleaksmey Lorn, Sophy Chy, Jean Popovici, Amélie Vantaux, Benoit Witkows, Antoine Berry, Patrice Piola, Claude Flamand.
The Lancet Regional Health – Western Pacific Volume 47, June 2024, 101093 https://doi.org/10.1016/j.lanwpc.2024.101093
In Vitro Antimalarial Activity of Trichothecenes against Liver and Blood Stages of Plasmodium
Parvatkar PT, Maher SP, Zhao Y, Cooper CA, de Castro ST, Péneau J, Vantaux A, Witkowski B, Kyle DE, Manetsch R.
J Nat Prod. 2024 Jan 23. doi: 10.1021/acs.jnatprod.3c01019. Online ahead of print
David Guerrero, Sokchea Lay, Eakpor Piv, Chansophea Chhin, Sokkeang Leng, Ratana Meng, Kim Eng Mam, Polidy Pean, Amelie Vantaux, Sebastien Boyer, Dorothée Missé, Tineke CantaertOxford Open Immunology, Volume 5, Issue 1, 2024, iqae003. Advance Access Publication Date: 1 April 2024 https://doi.org/10.1093/oxfimm/iqae003
Marcombe S, Doeurk B, Thammavong P, Veseli T, Heafield C, Mills MA, Kako S, Prado MF, Thomson S, Millett S, Hill T, Kentsley I, Davies S, Pathiraja G, Daniels B, Browne L, Nyamukanga M, Harvey J, Rubinstein L, Townsend C, Allen Z, Davey-Spence C, Hupi A, Jones AK, Boyer S.
2024 May 15; https://doi.org/10.3390/insects15050358 PMID: 38786914
Claire L. Jeffries, Luciano M Tantely, Perparim Kadriaj, Marcus S C Blagrove, Loanna Lytra, James Orsborne, Hasan Mohammad Al-Amin, Abdul Rahim Mohammed, Mohammad Shafiul Alam, Romain Girod, Yaw A Afrane, Silvia Bino, Vincent Robert, Sebastien Boyer, Matthew Baylis, Enkelejda Velo, Grant L Hughes, Thomas Walker
Wellcome Open Research 2024, 9:18 Last updated: 01 APR 2024 https://doi.org/10.12688/wellcomeopenres.20761.1
Leblanc C, Kassié D, Ranaivoharimina M, Rakotomanana EFN, Mangahasimbola RT, Randrianarijaona A, Ramiandrasoa R, Nely AJ, Razafindraibe NP, Andriamandimby SF, Ranoaritiana DB, Rajaonarivony V, Randrianasolo L, Baril L, Mattern C, Ratovoson R, Guis H.
PLoS Negl Trop Dis. 2024 Mar 29;18(3):e0012064. doi: 10.1371/journal.pntd.0012064. Online ahead of print. PMID: 38551968
Multilocus sequence typing of clinical Burkholderia pseudomallei isolates from Cambodia.
Gyamfi E, Delvallez G, Cheng S, Meng S, Oeurn K, Sam C, Kerleguer A, Guillard B, Bañuls AL, Hide M. – PLoS Negl Trop Dis. 2024 Nov 14;18(11):e0012652. doi: 10.1371/journal.pntd.0012652.
Bernard C, Mané I, Ziadeh S, Tine JM, Diaw A, Benzekri N, Ndiaye I, Samba O, Font H, Bottai T, Jacquesy L, Verdeli H, Ngom NF, Dabis F, Seydi M, de Rekeneire N.
Front Public Health. 2024 Jan 24;12:1295181. doi: 10.3389/fpubh.2024.1295181.
Joste V, Coppée R, Bailly J, Rakotoarivony Y, Toko Tchokoteu FG, Achache S, Pradines B, Cottrell G, Ariey F, Khim N, Popovici J, Mita T, Groger M, Ramharter M, Egbo T, Juma DW, Akala H, Houzé S, Clain J; Investigation Study Group.
Lancet Microbe. 2024 May, https://doi.org/10.1016/s2666-5247(24)00054-5 . PMID: 38761813
Plasmodium vivax spleen-dependent protein 1 and its role in extracellular vesicles-mediated intrasplenic infections. Ayllon-Hermida A, Nicolau-Fernandez M, Larrinaga AM, Aparici-Herraiz I, Tintó-Font E, Llorà-Batlle O, Orban A, Yasnot MF, Graupera M, Esteller M, Popovici J, Cortés A, Del Portillo HA, Fernandez-Becerra C.Front Cell Infect Microbiol. 2024 May 17;14:1408451. https://doi.org/10.3389/fcimb.2024.1408451 . eCollection 2024.PMID: 38828264
Winnicki AC, Dietrich MH, Yeoh LM, Carias LL, Roobsoong W, Drago CL, Malachin AN, Redinger KR, Feufack-Donfack LB, Baldor L, Jung NC, McLaine OS, Skomorovska-Prokvolit Y, Orban A, Opi DH, Kirtley P, Nielson K, Aleshnick M, Zanghi G, Rezakhani N, Vaughan AM, Wilder BK, Sattabongkot J, Tham WH, Popovici J, Beeson JG, Bosch J, King CL Nat Commun. 2024 Dec 4;15(1):10556. doi: 10.1038/s41467-024-53848-4.
Martinez FJ, White M, Guillotte-Blisnick M, Huon C, Boucharlat A, Agou F, England P, Popovici J, Hou MM, Silk SE, Barrett JR, Nielsen CM, Reimer JM, Mukherjee P, Chauhan VS, Minassian AM, Draper SJ, Chitnis CE.
NPJ Vaccines. 2024 Jan 6;9(1):10. doi: 10.1038/s41541-023-00796-7.
Rapid decrease in IL-1Ra and IP-10 plasma levels following tuberculosis treatment initiation
Pean Polidy, Roseline Affi, Corine Chazalon, Ben Cheick Soumahoro, Delphine Gabillard, Dim Bunnet, Laurence Borand, Raoul Moh, Xavier Anglaret, François-Xavier Blanc, Pierre-Marie Girard, Guislaine Carcelain, Didier Laureillard, Laurence Weiss
International Journal of Infectious Diseases Available online 11 May 2024, 107096 https://doi.org/10.1016/j.ijid.2024.107096
Doeurk B, Marcombe S, Maquart PO, Boyer S.
Parasit Vectors. 2024 Oct 9;17(1):424. doi: 10.1186/s13071-024-06481-5.
Jee-Seon Yang, Saren Sovann, Yusuke Shimakawa, Sovann Nhoueng, Bunnet Dim, Chanlina Vong, Channa Sann, Julia Guillebaud, Darapolin Vann, Bunrith Touch, Hyna Chea, Wathanak Pisey Choupoan Phirum, Eric Rosenthal , Christelle Paul, Leangchhun Khun, Chantana Yay, Denis Laurent, Samsorphea Chhun, Laurence Borand and Olivier Segeral
Viruses 2024, 16(2), 194; https://www.mdpi.com/1999-4915/16/2/194
Benjamin L. Sievers, Jurre Y. Siegers, Jimmy M. Cadènes, Sudipta Hyder, Frida E. Sparaciari, Filip Claes, Cadhla Firth, Paul F. Horwood, Erik A. Karlsson
Journal of Virology 16 January 2024 DOI: https://journals.asm.org/doi/10.1128/jvi.01683-23
Speciation patterns of Aedes mosquitoes in the Scutellaris Group: a mitochondrial perspective
Antsa Rakotonirina, Catherine Dauga, Morgane Pol, Mallorie Hide, Linavin Vuth, Valentine Ballan, Sosiasi Kilama, Sylvie Russet, Sébastien Marcombe, Sébastien Boyer & Nicolas Pocquet
Scientific Reports volume 14, Article number: 10930 (2024) https://doi.org/10.1038/s41598-024-61573-7
The genetic diversity of Nipah virus across spatial scales.
Cortes-Azuero O, Lefrancq N, Nikolay B, McKee C, Cappelle J, Hul V, Ou TP, Hoem T, Lemey P, Rahman MZ, Islam A, Gurley ES, Duong V, Salje H.
J Infect Dis. 2024 Apr 29:jiae221. doi: 10.1093/infdis/jiae221. Online ahead of print. PMID: 38682164
Feufack-Donfack LB, Baldor L, Roesch C, Tat B, Orban A, Seng D, Salvador J, Khim N, Carias L, KingCL, Russell B, Nosten F, Ong AS, Mao H, Renia L, Lo E, Witkowski B, Popovici J. NPJ Vaccines. 2024 Nov 22;9(1):232. doi: 10.1038/s41541-024-01031-7.
Unraveling the intricacies of host-pathogen interaction through single-cell genomics.
Gioacchino E, Vandelannoote K, Ruberto AA, Popovici J, Cantaert T.
Microbes Infect. 2024 Feb 16:105313. doi: 10.1016/j.micinf.2024.105313.
Forsans, M.-A. Tareau, L. Ramiz, C. Alves Sarmento, N. Clément, A. Perilhou, N. Vignier, G. Odonne, M. Nacher, C. Flamand
Journal of Herbal Medicine Volume 44, March 2024, 100848 DOI : 10.1016/j.hermed.2024.100848
Using serological diagnostics to characterize remaining high-incidence pockets of malaria in forest-fringe Cambodia.
Grimée M, Tacoli C, Sandfort M, Obadia T, Taylor AR, Vantaux A, Robinson LJ, Lek D, Longley RJ, Mueller I, Popovici J, White MT, Witkowski B.
Viromes of arthropod parasites and their hosts: The case of bats and bat ectoparasites.
Tendu A, Li R, Kane Y, Nalikka B, Omondi V, Bienes KM, Berthet N, Wong G. Acta Trop. 2024 Sep 1;259:107375. doi: 10.1016/j.actatropica.2024.107375. Online ahead of print.
We need a global framework for promoting safe handling of high consequence pathogens.
Karlsson EA, Blacksell SD, Carroll D, Harper DR, Morzaria S, Claes F.
BMJ. 2024 Aug 23;386:q1855. doi: 10.1136/bmj.q1855.
Malar J. 2024 Feb 15;23(1):49. doi: 10.1186/s12936-024-04859-5.
Roth C, Pitard B, Levillayer L, Lay S, Vo HTM, Cantaert T, Sakuntabhai A. PLoS Negl Trop Dis. 2024 Oct 17;18(10):e0012601. doi: 10.1371/journal.pntd.0012601.
A Qualitative Study of the Experience of COVID-19 Patients in Burkina Faso.
Konaté B, Médah R, Traoré I, Ouedraogo S, Kaboré NF, Mamguem AK, Billa O, Kania D, Badolo H, Ouédraogo E, de Rekeneire N, Poda A, Diendéré AE, Ouédraogo B, Tinto H, Dabakuyo-Yonli TS.
Am J Trop Med Hyg. 2023 Dec 18;110(1):170-178. doi: 10.4269/ajtmh.22-0351.
Basant Joshi, Yara Voss De Lima, Douglas Mbang Massom, Sanary Kaing, Marie-France Banga, Egerton Tamba Kamara, Sheriff Sesay, Laurence Borand, Jean-Voisin Taguebue, Raoul Moh, Celso Khosa, Guillaume Breton, Juliet Mwanga-Amumpaire, Maryline Bonnet, Eric Wobudeya, Olivier Marcy, Joanna Orne-Gliemann, the TB-Speed Decentralization study group
PLOS Public and Global Health Pub Date: 2023-10-11 , DOI:10.1101/2023.01.04.23284184
Adam M, Nahzat S, Kakar Q, Assada M, Witkowski B, Tag Eldin Elshafie A, Abuobaida D, Safi N, Khan MA, Nagi M, Mustafa SA, Kohestani K, Muhammad J, Khim N, Al-Hadi M, Elfaki TM, Habib MN, Khairy AKA, Hamid H, Uddin Z, Amer Y, Hassan AH, Elhag MS, Sediqi AW, Kakar I, Abdul-Ghani R, Amran JGH, Abdallrahim TA, Tamim MS, Aljasari A, Rasmussen C, Azkoul L, Warsame M.
Trop Med Int Health. 2023;28(10):817-29. doi: 10.1111/tmi.13929
Arbovirus researchers unite: expanding genomic surveillance for an urgent global need
Gabriel Luz Wallau Author links open overlay panelNgu Njei Abanda, Adriano Abbud, Saro Abdella, Adugna Abera, Steve Ahuka-Mundeke, Francesca Falconi-Agapito, Kalichamy Alagarasu, Kevin K Ariën, Constancia Flávia Junqueira Ayres, Luisa Barzon, Joseph Humphrey Kofi Bonney, Sanaba Boumbaly, Philippe Buchy, Van-Mai Cao-Lormeau, Yu Kie Chem, Paul A Cardenas, Andres E Castillo, Adriana Delfraro, Gregor Devine, Veasna Duong, Myrielle Dupont-Rouzeyrol, Artem V Fadeev, Alvaro Fajardo, Luis Adrián Diaz, Lara Ferrero Gómez, Eduardo Samo Gudo, Gladys Gutierrez-Bugallo, Hapuarachchige Chanditha Hapuarachchi, Jean-Michel Heraud, Martin L Hibberd, Osvaldo Frederico Inlamea, Nik Jasmin, Kalysbek Kydyshov, Maria Ezekiely Kelly, Salim Khan, Andrey B Komissarov, Pornsawan Leaungwutiwong, Mariana Leguia, Yaniv Lustig, Rafael Maciel-de-Freitas, Gathsaurie Neelika Malavige, Alexander A Martinez, Maria L Mendoza, Luong T Mo, Brechla Moreno, Lydia Mwasi, Felipe Gomes Naveca, Lee Ching NG, Richard Njouom, Mauricio Lacerda Nogueira, Francine Ntoumi, Nehemie Nzoyikorera, Barbara A Parra, Mauricio Vázquez Pichardo, Kristine Joy Ragual Privaldos, Ricardo Rivero, Alejandra María Rojas, Richard Steiner Salvato, R Tedjo Sasmono, Jonas Schmidt-Chanasit, Etienne Simon-Loriere, Ava Kristy Dy Sy, Michael Talledo-Albujar, Daniel Thakuma Tizhe, Usenbaev Nurbolot Toloshovich, Vi Thuy Tran, Cécile Troupin, John Timothy Kayiwa, Andrew van den Hurk, Nikolaos Vasilakis, Atsbeha Gebreegziabxier Weldemariam, Sophie Yacoub, Zainun Zaini, Gabriel Luz Wallau
The Lancet Global Health 2023-08-01 DOI : 10.1016/S2214-109X(23)00325-X
Characterization of soluble TLR2 and CD14 levels during acute dengue virus infection.
Upasani V, Ter Ellen BM, Sann S, Lay S, Heng S, Laurent D, Ly S, Duong V, Dussart P, Smit JM, Cantaert T, Rodenhuis-Zybert IA.
Heliyon. 2023 Jun 21;9(6):e17265. doi: 10.1016/j.heliyon.2023.e17265. eCollection 2023 Jun.
Delvallez G, Cheng S, Marot S, Malonga GA, Cocherie T, Wignall S, Calvez V, Phal S, Vichet K, Marcelin AG, Jary A.
Open Forum Infect Dis. 2023 Oct 31;10(11):ofad540. doi: 10.1093/ofid/ofad540. eCollection 2023 Nov.
Chaolun Liu, Mingzhe Guo, Lin Han, Jie Lu, Xiaogang Xiang, Qing Xie, Janin Nouhin, Veasna Duong, Yimin Tong, Jin Zhong
J Med Virol. 2023 Sep;95(9):e29103. doi: 10.1002/jmv.29103.
Pierre-Olivier Maquart, Nil Rahola, Kalyan Chhuoy, Kimly Heng, Moeun Chhum, Kimhuor Suor, Sébastien Boyer
Journal of Asia-Pacific Entomology 26 (2023) 102064 DOI : 10.1016/j.aspen.2023.102064
Jurre Y. Siegers, Michelle Wille, Sokhoun Yann, Songha Tok, Sarath Sin, Sokha Chea, Alice Porco, Sreyem Sours, Vutha Chim, Samban Chea, Kimtuo Chhel, Sothyra Tum, Sorn San, Peter Thielen, Vijaykrishna Dhanasekaran, Erik A. Karlsson
Emerging Microbes & Infections DOI: 10.1080/22221751.2023.2297552
Pedro Jimenez-Bluhm, Jurre Y. Siegers, Shaoyuan Tan, Bridgett Sharp, Pamela Freiden, Magdalena Johow, Katherinne Orozco, Soledad Ruiz, Cecilia Baumberger, Pablo Galdames, Maria Antonieta Gonzalez, Camila Rojas, Erik A. Karlsson, Christopher Hamilton-West, Stacey Schultz-Cherry
Emerging Microbes & Infections https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2220569
Detection of Clade 2.3.4.4b Avian Influenza A(H5N8) Virus in Cambodia, 2021
Kimberly M Edwards, Jurre Y Siegers, Xiaoman Wei, Ammar Aziz, Yi-Mo Deng, Sokhoun Yann, Chan Bun, Seng Bunnary, Leonard Izzard, Makara Hak, Peter Thielen, Sothyra Tum, Frank Wong, Nicola S Lewis, Joe James, Filip Claes, Ian G Barr, Vijaykrishna Dhanasekaran, Erik A Karlsson
Emerg Infect Dis. 2023 Jan;29(1):170-174. doi: 10.3201/eid2901.220934.
‘Forest malaria’ in Myanmar? Tracking transmission landscapes in a diversity of environments.
Eva Legendre, Florian Girond, Vincent Herbreteau, Sokeang Hoeun, Stanislas Rebaudet, Aung Myint Thu, Jade Dean Rae, Laurent Lehot, Sokhna Dieng, Gilles Delmas, François Nosten, Jean Gaudart & Jordi Landier
Parasit Vectors. 2023 Sep 12;16(1):324. doi: 10.1186/s13071-023-05915-w.
Nardella F, Dobrescu I, Hassan H, Rodrigues F, Thiberge S, Mancio-Silva L, Tafit A, Jallet C, Cadet-Daniel V, Goussin S, Lorthiois A, Menon Y, Molinier N, Pechalrieu D, Long C, Sautel F, Matondo M, Duchateau M, Médard G, Witkowski B, Scherf A, Halby L, Arimondo PB.
iScience. 2023 Jan 11;26(2):105940. doi: 10.1016/j.isci.2023.105940. eCollection 2023 Feb 17.
Maryline Bonnet, Delphine Gabillard, Serge Domoua, Conrad Muzoora, Eugène Messou, Samreth Sovannarith, Duc Bang Nguyen, Anani Badje, Sylvain Juchet, Dim Bunnet, Laurence Borand, Naome Natukunda, Thị Hong Tran, Xavier Anglaret, Didier Laureillard, François-Xavier Blanc;
Clin Infect Dis. 2023 Mar 8;ciad125. doi: 10.1093/cid/ciad125.
Human FcγRIIIa activation on splenic macrophages drives dengue pathogenesis in mice
Yamin R, Kao KS, MacDonald MR, Cantaert T, Rice CM, Ravetch JV, Bournazos S.
Nat Microbiol. 2023 Aug;8(8):1468-1479. doi: 10.1038/s41564-023-01421-y. Epub 2023 Jul 10.
Janin Nouhin, Philip Lei Tzou, Soo-Yon Rhee, Malaya K. Sahoo, Benjamin A. Pinsky, Miri Krupkin, Joseph D. Puglisi, Elisabetta V. Puglisi, Robert W. Shafer
Journal of General Virology Published: 06 October 2023 https://doi.org/10.1099/jgv.0.001898
Quentin D. Watson, Lenore L. Carias, Alyssa Malachin, Karli R. Redinger, Jürgen Bosch, Martino Bardelli, Lea Baldor, Lionel Brice Feufack-Donfack, Jean Popovici, Robert W. Moon, Simon J. Draper, Peter A. Zimmerman & Christopher L. King
Malar J. 2023 Dec 4;22(1):369. doi: 10.1186/s12936-023-04766-1.
Francisco J Martinez, Micheline Guillotte-Blisnick, Christèle Huon, Patrick England, Jean Popovici, Hélène Laude, Laurence Arowas, Marie-Noëlle Ungeheuer, Jenny M Reimer, Darrick Carter, Steve Reed, Paushali Mukherjee, Virander S Chauhan, Chetan E Chitnis
Sci Rep. 2023 Aug 25;13(1):13904. doi: 10.1038/s41598-023-40043-6.
Antoine Ardillon, Lison Ramblière, Elsa Kermorvant-Duchemin, Touch Sok, Andrianirina Zafitsara Zo, Jean-Baptiste Diouf, Pring Long, Siyin Lach, Fatoumata Diene Sarr, Laurence Borand, Felix Cheysson, Jean-Marc Collard, Perlinot Herindrainy, Agathe de Lauzanne, Muriel Vray, Elisabeth Delarocque-Astagneau, Didier Guillemot, Bich-Tram Huynh; BIRDY study group
PLoS Med. 2023 Jun 6;20(6):e1004211. doi: 10.1371/journal.pmed.1004211. eCollection 2023 Jun
Benjamin L Sievers, Robert E Sievers, Eric L Sievers
Open Forum Infect Dis. 2023 Jun 5;10(6):ofad302. doi: 10.1093/ofid/ofad302. eCollection 2023 Jun.
Nilandone Senvanpan, Vilayouth Phimolsarnnousith, Sayaphet Rattanavong, Mayfong Mayxay, Daniel Reinharz, Amanda E Fine, Paul F Horwood, Philippe Dussart, Stuart D Blacksell, Mathieu Pruvot, Paul N Newton, Matthew T Robinson
One Health. 2023 Aug 25:17:100618. doi: 10.1016/j.onehlt.2023.100618. eCollection 2023 Dec.
Longitudinal Study of Viral Diversity Associated with Mosquito Species Circulating in Cambodia
Souand Mohamed Ali, Antsa Rakotonirina, Kimly Heng, Elise Jacquemet, Stevenn Volant, Sarah Temmam, Sebastien Boyer and Marc Eloit
Viruses 2023, 15, 1831. https://doi.org/10.3390/v15091831
Malaria temporal dynamic clustering for surveillance and intervention planning
Eva Legendre , Laurent Lehot, Sokhna Dieng , Stanislas Rebaudet, Aung Myint Thu, Jade D Rae, Gilles Delmas, Florian Girond, Vincent Herbreteau, François Nosten, Jordi Landier, Jean Gaudart
Epidemics . 2023 Jun;43:100682. doi: 10.1016/j.epidem.2023.100682. Epub 2023 Mar 27.
Bernard C, Font H, Ziadeh S, Tine JM, Diaw A, Ndiaye I, Samba O, Bottai T, Jacquesy L, Verdeli H, Ngom NF, Dabis F, Seydi M, de Rekeneire N; IeDEA West Africa Cohort Collaboration.
Glob Ment Health (Camb). 2023 Jun 30;10:e36. doi: 10.1017/gmh.2023.31. eCollection 2023.
Mosquito diversity (Diptera: Culicidae) and medical importance in four Cambodian forests
Antsa Rakotonirina, Pierre-Olivier Maquart, Claude Flamand, Chea Sokha & Sébastien Boyer
Parasites & Vectors 2023-03-21 DOI : 10.1186/s13071-023-05729-w
National dengue surveillance, Cambodia 2002-2020
Christina Yek, Yimei Li, Andrea R Pacheco, Chanthap Lon, Veasna Duong, Philippe Dussart, Katherine I Young, Sophana Chea, Sreyngim Lay, Somnang Man, Souv Kimsan, Chea Huch, Rithea Leang, Rekol Huy, Cara E Brook, Jessica E Manning
Bull World Health Organ. 2023 Sep 1;101(9):605-616. doi: 10.2471/BLT.23.289713. Epub 2023 Jul 5.
Natural Killer Repertoire Restoration in TB/HIV Co-Infected Individuals Experienced an Immune Reconstitution Syndrome (CAMELIA Trial, ANRS 12153).
Pean P, Madec Y, Nerrienet E, Borand L, Laureillard D, Fernandez M, Marcy O, Scott-Algara D; CAMELIA Study Team.
Pathogens. 2023 Oct 13;12(10):1241. doi: 10.3390/pathogens12101241.
Surafel K Tebeje, Wakweya Chali, Elifaged Hailemeskel, Jordache Ramjith, Abrham Gashaw, Temesgen Ashine, Desalegn Nebret, Endashaw Esayas, Tadele Emiru, Tizita Tsegaye, Karina Teelen, Kjerstin Lanke, Eizo Takashima, Takafumi Tsuboi, Nichole D Salinas, Niraj H Tolia, David Narum, Chris Drakeley, Benoit Witkowski, Amelie Vantaux, Matthijs M Jore, William J R Stone, Ivo S Hansen, Fitsum G Tadesse, Teun Bousema
Front Cell Infect Microbiol. 2023 Jan 16:12:1106369. doi: 10.3389/fcimb.2022.1106369. eCollection 2022
Neutralization of African enterovirus A71 genogroups by antibodies to canonical genogroups.
Volle R, Luo L, Razafindratsimandresy R, Sadeuh-Mba SA, Gouandjika-Valisache I, Horwood P, Duong V, Buchy P, Joffret ML, Huang Z, Duizer E, Martin J, Chakrabarti LA, Dussart P, Jouvenet N, Delpeyroux F, Bessaud M.
J Gen Virol. 2023 Nov;104(11). doi: 10.1099/jgv.0.001911.
Obesity Is Associated with an Impaired Baseline Repertoire of Anti-Influenza Virus Antibodies
Marwa Abd Alhadi, Lilach M. Friedman, Erik A. Karlsson, Liel Cohen-Lavi, Anat Burkovitz, Stacey Schultz-Cherry, Terry L. Noah, Samuel S. Weir, Lester M. Shulman, Melinda A. Beck, Tomer Hertz
Microbiology Spectrum 26 April 2023 DOI: https://doi.org/10.1128/spectrum.00010-23
One assay to test them all: Multiplex assays for expansion of respiratory virus surveillance
Narjis Boukli, Claude Flamand, Kim Lay Chea, Leangyi Heng, Seangmai Keo, Kimhoung Sour, Sophea In, Panha Chhim, Bunthea Chhor, Lomor Kruy, Jelena D. M. Feenstra, Manoj Gandhi, Obiageli Okafor, Camilla Ulekleiv, Heidi Auerswald, Viseth Srey Horm and Erik A. Karlsson
Front. Med., 24 April 2023 doi.org/10.3389/fmed.2023.1161268
Rutaiwan Dusadeepong, Gauthier Delvallez, Sokleaph Cheng, Soda Meng, Navin Sreng, Joanne Letchford, Kimcheng Choun, Syna Teav, Liselotte Hardy, Jan Jacobs, Tuyet Hoang, Torsten Seemann, Benjamin P Howden, Philippe Glaser, Timothy P Stinear, Koen Vandelannoote
Microb Genom. 2023 Mar;9(3). doi: 10.1099/mgen.0.000972.
Phylogeny and spatial distribution of Japanese encephalitis virus vector species in Cambodia
Dusadeepong R, Maquart PO, Hide M, Boyer S.
Med Vet Entomol. 2023 Jul 5. doi: 10.1111/mve.12678. Online ahead of print.
Plasmodium vivax Malaria in Duffy-Positive Patients in Rwanda.
Welmoed van Loon, Rafael Oliveira , Clara Bergmann, Felix Habarugira, Costanza Tacoli, Julia Jäger, Darius Savelsberg, Djibril Mbarushimana, Jules M Ndoli, Augustin Sendegeya, Claude Bayingana, Frank P Mockenhaupt
Am J Trop Med Hyg. 2023 Aug 7:tpmd230143. doi: 10.4269/ajtmh.23-0143. Online ahead of print.
Plugging the leaks: antibiotic resistance at human–animal interfaces in low-resource settings
Maya L Nadimpalli, Marc Stegger, Roberto Viau, Vuthy Yith, Agathe de Lauzanne, Nita Sem, Laurence Borand, Bich-tram Huynh, Sylvain Brisse, Virginie Passet, Søren Overballe-Petersen, Maliha Aziz, Malika Gouali, Jan Jacobs, Thong Phe, Bruce A Hungate, Victor O Leshyk, Amy J Pickering, François Gravey, Cindy M Liu, Timothy J Johnson, Simon Le Hello, Lance B Price
Frontiers in Ecology and the Environment; sept 2023 doi: 10.1002/fee.2639
Mairet-Khedim M, Roesch C, Khim N, Srun S, Bouillon A, Kim S, Ke S, Kauy C, Kloeung N, Eam R, Khean C, Kul C, Chy S, Leang R, Ringwald P, Barale JC, Witkowski B.
J Antimicrob Chemother. 2023;78(2):411-7. doi: 10.1093/jac/dkac403
Jary A, Cheng S, Marot S, Malonga GA, Cocherie T, Wignall S, Calvez V, Phal S, Vichet K, Marcelin AG, Delvallez G.
The Journal of Infection 2023 Feb 28;S0163-4453(23)00124-X. DOI: 10.1016/j.jinf.2023.02.038
Amani Ghousein, Jordan Tutagata, Hans Schrieke, Manuel Etienne, Victor Chaumeau, Sebastien Boyer, Nonito Pages, David Roiz, A Murat Eren, Guillaume Cambray, Julie Reveillaud
ISME Commun. 2023 Apr 28;3(1):40. doi: 10.1038/s43705-023-00248-2
Rabies surveillance in Madagascar from 2011 to 2021: can we reach the target?
Andriamandimby SF, Volasoa MH, Razafindraibe NP, Ranoaritiana DB, Razafindramparany MH, Rafisandratantsoa T, Nomenjanahary LA, Rakotondrabe N, Andriamananjara MA, Guis H, Lacoste V, Dreyfus A.
Front Vet Sci. 2023 Oct 12;10:1270532. doi: 10.3389/fvets.2023.1270532. eCollection 2023.
Cassandra Koh, Lionel Frangeul, Hervé Blanc, Carine Ngoagouni, Sébastien Boyer , Philippe Dussart, Nina Grau, Romain Girod, Jean-Bernard Duchemin, Maria-Carla Saleh
Elife. 2023 Jan 23;12:e82762. doi: 10.7554/eLife.82762.
Heidi Auerswald, Alvino Maestri, Sothy Touch, Saraden In, Nisa Ya, Borita Heng, Valérie Bosch-Castells, Christele Augard, Céline Petit, Philippe Dussart, Yiksing Peng, Tineke Cantaert, Sowath Ly
Clin Infect Dis. 2023 Jun 20;ciad304. doi: 10.1093/cid/ciad304
Mathieu Pruvot, Sokha Chea, Vibol Hul, Samat In, Vuthy Buor, Jill Lea Ramassamy, Caroline Fillieux, Seng Sek, Ratha Sor, Sela Ros, Sithun Nuon, Sovannary San, Yaren Ty, Marany Chao, SreyemSours, Sreyleap Torng, Unthyda
Choeurn, Udam Hun, Sophorn Ton, Samnang Y, Sonara Phon, Lina Kuy, Amanda Fine, Philippe Dussart, Veasna Duong, Paul F. Horwood, Sarah H. Olson
One Earth, Available online 29 November 2023. 10.1016/j.oneear.2023.11.003
Stag beetle fauna of Cambodia (Coleoptera: Lucanidae)
Maquart PO, Yamamoto S, Sopha S, Chhorn S, Phak S, Sinovas P, Phauk S, Boyer S.
Journal of Asia Pacific Entomology 26(2023) 102008 https://doi.org/10.1016/j.aspen.2022.102008
Koen Vandelannoote, Andrew H Buultjens, Jessica L Porter, Anita Velink, John R Wallace, Kim R Blasdell, Michael Dunn, Victoria Boyd, Janet AM Fyfe, Ee Laine Tay, Paul DR Johnson, Saras M Windecker, Nick Golding, Timothy P Stinear
eLife Apr 14, 2023 https://elifesciences.org/articles/84983
Stillbirths and neonatal mortality in LMICs: A community-based mother-infant cohort study
Lison Rambliere, Agathe de Lauzanne, Jean-Baptiste Diouf, Andrianirina Zafitsara Zo, Myriam Landau, Perlinot Herindrainy, Delphine Hivernaud, Fatoumata Diene Sarr, Touch Sok, Muriel Vray, Jean-Marc Collard, Laurence Borand, Elisabeth Delarocque-Astagneau, Didier Guillemot, Elsa Kermorvant-Duchemin, Bich-Tram Huynh; BIRDY study group
J Glob Health. 2023 Apr 14;13:04031. doi: 10.7189/jogh.13.04031
Mirco Sandfort, Wuelton Monteiro, Marcus Lacerda , Wang Nguitragool, Jetsumon Sattabongkot, Andreea Waltmann, Henrik Salje, Amélie Vantaux, Benoit Witkowski, Leanne J Robinson, Ivo Mueller, Michael White
Malaria Journal 2023 Mar 4;22(1):75. DOI: 10.1186/s12936-023-04515-4
Sotheara Moeung, François Chassagne, Sophie Goyet, Sovann Nhoeung, Lynecta Sun, Dorina Yang, Steve Vilhem, Bunnet Dim, Socheat Ly, Linda Sov, Vouchleang Sreng, Sokda Chorn, Samsorphea Chhun, Laurence Borand, Sothea Kim, Olivier Segeral
PLoS One. 2023 Aug 10;18(8):e0288389. doi: 10.1371/journal.pone.0288389. eCollection 2023.
Uncovering the endemic circulation of rabies in Cambodia
Maylis Layan, Laurent Dacheux, Philippe Lemey, Kirstyn Brunker, Laurence Ma, Cécile Troupin, Philippe Dussart, Véronique Chevalier, James L. N. Wood, Sowath Ly, Veasna Duong, Hervé Bourhy, Simon Dellicour
Molecular Ecology 04 August 2023 DOI : 10.1111/mec.17087
Florian Verrier, Agathe de Lauzanne, Jean-Baptiste Niokhhor Diouf, Andrianirina Zafitsara Zo, Lison Ramblière, Perlinot Herindrainy, Fatoumata Diene Sarr, Touch Sok, Muriel Vray, Jean-Marc Collard, Laurence Borand, Elsa Kermorvant-Duchemin, Elisabeth Delarocque-Astagneau, Didier Guillemot, Bich-Tram Huynh; Bacterial Infections and Antibiotic-Resistant Diseases Among Young Children in Low-Income Countries (BIRDY) Study Group
Open Forum Infect Dis. 2023 Mar 10;10(4):ofad136. doi: 10.1093/ofid/ofad136. eCollection 2023 Apr.
